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Hereditary Spastic Paraparesis also known as HSP is a rare neurodegenerative disease. HSP is caused by the degeneration of motor neurons. In some cases brain MRI's have shown changes to the corpus callosum. HSP can become present at any time in the lifespan of the patient. There are two types of HSP complex and simple. The symptoms of simple HSP include problems walking, unnormal bladder problems and vibrations from the lower legs. On the other hand, complex HSP has the same symptoms of simple HSP plus a variety of other symptoms including cognitive issues such as learning and problem-solving issues, skin abnormalities, digestive, breathing and hearing abnormalities. HSP is a genetic disease caused by many SP genes. HSP has no cure but HSP training can dampen symptoms. Image Source: American Journal of Neuroradiology
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April 2020
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